Publications

 


Acknowledging the Resource

Please acknowledge contributions of the Quantitative Elemental Mapping for the Life Sciences Resource with text similar to this when publishing:

This research was carried out in collaboration with the Resource for Quantitative Elemental Mapping for the Life Sciences under Grant P41 GM135018 from the National Institute of General Medical Sciences of the National Institutes of Health.

2025

Schnizlein MK, Hong B, Nguyen JNT, Jones K, Rodriguez AI, Fiebig A, Campagna SR, Balunas MJ, O’Halloran TV, Crosson S. Non-redundant cardiolipin synthases shape membrane composition and support stress resilience in Bacteroides fragilis. bioRxiv 2025.05.12.653583; doi: https://doi.org/10.1101/2025.05.12.653583.

Balough JL, O’Halloran TV, Duncan FE, Woodruff TK. Inorganic profiles of preimplantation embryos reveal a role for zinc in blastocyst development. bioRxiv 2025.05.14.654061; doi: https://doi.org/10.1101/2025.05.14.654061.

Jiang Y, Nikolovski M, Wang T, MacRenaris KW, O’Halloran TV, Hu J. Targeting the selectivity filter to drastically alter the activity and substrate spectrum of a promiscuous metal transporter. bioRxiv 2025.05.07.652779; doi: https://doi.org/10.1101/2025.05.07.652779.

Crawford AM, Zee DZ, Jin Q, Sue A, Sinha N, Ahn SH, O’Halloran TV, MacRenaris KW. AutoSpect: An All-In-One Software Solution for Automated Processing of LA-ICP-TOF-MS datasets. bioRxiv 2025.05.09.653091; doi: https://doi.org/10.1101/2025.05.09.653091.

Kim T, Hong B, O’Halloran TV, Lisabeth E, Neubig RR, Fiebig A, Crosson S. Reversion of a RND transporter pseudogene uncovers latent stress resistance in Brucella ovis. bioRxiv 2025.05.10.653276; doi: https://doi.org/10.1101/2025.05.10.653276.

Ahn SH, Halgren K, Grzesiak G, MacRenaris KW, Sue A, Xie H, Demireva E, O'Halloran TV, Petroff MG. Autoimmune regulator deficiency causes sterile epididymitis and impacts male fertility through disruption of inorganic physiology. J Immunol. 2025 Apr 23:vkaf054. doi: 10.1093/jimmun/vkaf054. Epub ahead of print. PMID: 40267393.

Hernandez-Ortiz S, Ok K, O'Halloran TV, Fiebig A, Crosson S. A co-conserved gene pair supports Caulobacter iron homeostasis during chelation stress. J Bacteriol. 2025 Apr 17;207(4):e0048424. doi: 10.1128/jb.00484-24. Epub 2025 Mar 14. PMID: 40084995; PMCID: PMC12004947.

Roter B, Crawford AM, Jin Q, Glowacki AT, Lai B, Marin FS, Maxey E, Shi X, Culotta VC, Wildeman AS, Patel NK, O'halloran TV, Jacobsen C. Multifunctional bending magnet beamline with a capillary optic for X-ray fluorescence studies of metals in tissue sections. bioRxiv [Preprint]. 2025 Jan 22:2025.01.18.633695. doi: 10.1101/2025.01.18.633695. PMID: 39896496; PMCID: PMC11785041.


2024

He W, MacRenaris KW, Griebel A, Kwesiga MP, Freitas E, Gillette A, Schaffer J, O'Halloran TV, Guillory II RJ. Semi-quantitative elemental imaging of corrosion products from bioabsorbable Mg vascular implants in vivo. Bioact Mater. 2024 Sep 24;43:225-239. doi: 10.1016/j.bioactmat.2024.07.023. PMID: 39386222; PMCID: PMC11462046.

Iskhakova K, Cwieka H, Meers S, Helmholz H, Davydok A, Storm M, Baltruschat IM, Galli S, Pröfrock D, Will O, Gerle M, Damm T, Sefa S, He W, MacRenaris K, Soujon M, Beckmann F, Moosmann J, O'Hallaran T, Guillory II RJ, Wieland DCF, Zeller-Plumhoff B, Willumeit-Römer R. Multi-modal investigation of the bone micro- and ultrastructure, and elemental distribution in the presence of Mg-xGd screws at mid-term healing stages. Bioact Mater. 2024 Sep 3;41:657-671. doi: 10.1016/j.bioactmat.2024.07.019. PMID: 39296873; PMCID: PMC11408010.

Halim A, Mondal SK, Al-Qadi N, Kenyon E, MacRenaris K, O'Halloran TV, Medarova Z, Moore A. Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases. J Vis Exp. 2024 Aug 23;(210). doi: 10.3791/66961. PMID: 39248512.

Jiang Y, MacRenaris K, O'Halloran TV, Hu J. Determination of metal ion transport rate of human ZIP4 using stable zinc isotopes. J Biol Chem. 2024 Aug 9:107661. doi: 10.1016/j.jbc.2024.107661. Epub ahead of print. PMID: 39128710.

Pawelec KM, Hix JML, Troia A, MacRenaris KW, Kiupel M, Shapiro EM. In vivo micro-computed tomography evaluation of radiopaque, polymeric device degradation in normal and inflammatory environments. Acta Biomater. 2024 Jun;181:222-234. doi: 10.1016/j.actbio.2024.04.031. Epub 2024 Apr 20. PMID: 38648912; PMCID: PMC11144086.


2023

Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A, Nejad FK, Mahmoodzadeh A, Sato T, Ramos-Alonso L, Romero AM, Martinez-Pastor MT, Jiang SC, Sah-Teli SK, Li L, Bentrem D, Lopaschuk G, Ben-Sahra I, O'Halloran TV, Shilatifard A, Puig S, Bergelson J, Koivunen P, Ardehali H. Iron Drives Anabolic Metabolism Through Active Histone Demethylation and mTORC1.Nat Cell Biol. 2023 Oct; 25(10):1478-1494. PMID: 37749225

Jiang, Yuhan; Li, Zhen; Sui, Dexin; Sharma, Gaurav; Wang, Tianqi; MacRenaris, Keith; Takahashi, Hideki; Merz, Kenneth; Hu, Jian. Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity. Communications Biology 2023 Jul 26; 6 (1) 778. PMID: 37495662; PMCID: PMC10372143

Chen Y, Chen S, Ok K, Duncan FE, O’Halloran TV, Woodruff TK. Zinc dynamics regulate early ovarian follicle development. JBC 2023 299(1): 102731. PMID: 36423685; PMCID: PMC9800340


2022

Chowdhury MAZ, Ok K, Luo Y, Liu Z, Chen S, O'Halloran TV, Kettimuthu R, Tekawade A. ROI-Finder: machine learning to guide region-of-interest scanning for X-ray fluorescence microscopy. J Synchrotron Research 2022 Nov 1;29 (Pt 6): 1495-1503. PMID: 36345757; PMCID: PMC9641565

Rong Q, Lee Y, Tang Y, Vu T, Taboada C, Zheng W, Xia J, Czaplewski DA, Zhang HF, Sun, C, Yao, J. High-Frequency 3D Photoacoustic Computed Tomography Using an Optical Microring Resonator. BME Frontiers 2022 Aug. https://doi.org/10.34133/2022/9891510

Song K, Brenner B, Yeo W, Kweon J, Cai Z, Zhang Y, Lee Y, Yang X, Sun C, Zhang HF. Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy. Nanophotonics 2022 11(8), 1527-1535. PMCID: PMC9307059 

Zee DZ, MacRenaris KW, O'Halloran TV. Quantitative imaging approaches to understanding biological processing of metal ions. Curr Opin Chem Biol. 2022 69: 102152. PMID: 35561425

Mendoza AD, Sue A, Antipova O, Vogt S, Woodruff TK, Wignall SM, O'Halloran TV. Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans. Biology of Reproduction August 2022 107(2). 406-418. PMID: 35466369


2021

Seeler JF, Sharma A, Zaluzec NJ, Bleher R, Lai B, Schultz EG, Hoffman BM, LaBonne C, Woodruff TK, O'Halloran TV. Metal ion fluxes controlling amphibian fertilization. Nature Chemistry2021 Jul;13(7): 683-691. PMID: 34155376; PMCID: PMC8475775

Cai Z, Zhang Y, Zhang Z, Song KH, Beckmann L, Djalilian A, Sun C, Zhang HF. Super-resolution imaging of flat-mounted whole mouse cornea. Exp Eye Res2021 Apr;205:108499. PMID: 33610603; PMCID: PMC8043998

Huang J, Ware HOT, Hai R, Shao G, Sun C. Conformal Geometry and Multimaterial Additive Manufacturing through Freeform Transformation of Building Layers. Advanced Materials2021 Mar;33(11):e2005672. PMID: 33533141; PMCID: PMC8245009