Publications
Schnizlein MK, Hong B, Nguyen JNT, Jones K, Rodriguez AI, Fiebig A, Campagna SR, Balunas MJ, O’Halloran TV, Crosson S. Non-redundant cardiolipin synthases shape membrane composition and support stress resilience in Bacteroides fragilis. bioRxiv 2025.05.12.653583; doi: https://doi.org/10.1101/2025.05.12.653583.
Balough JL, O’Halloran TV, Duncan FE, Woodruff TK. Inorganic profiles of preimplantation embryos reveal a role for zinc in blastocyst development. bioRxiv 2025.05.14.654061; doi: https://doi.org/10.1101/2025.05.14.654061.
Jiang Y, Nikolovski M, Wang T, MacRenaris KW, O’Halloran TV, Hu J. Targeting the selectivity filter to drastically alter the activity and substrate spectrum of a promiscuous metal transporter. bioRxiv 2025.05.07.652779; doi: https://doi.org/10.1101/2025.05.07.652779.
Crawford AM, Zee DZ, Jin Q, Sue A, Sinha N, Ahn SH, O’Halloran TV, MacRenaris KW. AutoSpect: An All-In-One Software Solution for Automated Processing of LA-ICP-TOF-MS datasets. bioRxiv 2025.05.09.653091; doi: https://doi.org/10.1101/2025.05.09.653091.
Kim T, Hong B, O’Halloran TV, Lisabeth E, Neubig RR, Fiebig A, Crosson S. Reversion of a RND transporter pseudogene uncovers latent stress resistance in Brucella ovis. bioRxiv 2025.05.10.653276; doi: https://doi.org/10.1101/2025.05.10.653276.
Ahn SH, Halgren K, Grzesiak G, MacRenaris KW, Sue A, Xie H, Demireva E, O'Halloran TV, Petroff MG. Autoimmune regulator deficiency causes sterile epididymitis and impacts male fertility through disruption of inorganic physiology. J Immunol. 2025 Apr 23:vkaf054. doi: 10.1093/jimmun/vkaf054. Epub ahead of print. PMID: 40267393.
Hernandez-Ortiz S, Ok K, O'Halloran TV, Fiebig A, Crosson S. A co-conserved gene pair supports Caulobacter iron homeostasis during chelation stress. J Bacteriol. 2025 Apr 17;207(4):e0048424. doi: 10.1128/jb.00484-24. Epub 2025 Mar 14. PMID: 40084995; PMCID: PMC12004947.
Roter B, Crawford AM, Jin Q, Glowacki AT, Lai B, Marin FS, Maxey E, Shi X, Culotta VC, Wildeman AS, Patel NK, O'halloran TV, Jacobsen C. Multifunctional bending magnet beamline with a capillary optic for X-ray fluorescence studies of metals in tissue sections. bioRxiv [Preprint]. 2025 Jan 22:2025.01.18.633695. doi: 10.1101/2025.01.18.633695. PMID: 39896496; PMCID: PMC11785041.
He W, MacRenaris KW, Griebel A, Kwesiga MP, Freitas E, Gillette A, Schaffer J, O'Halloran TV, Guillory II RJ. Semi-quantitative elemental imaging of corrosion products from bioabsorbable Mg vascular implants in vivo. Bioact Mater. 2024 Sep 24;43:225-239. doi: 10.1016/j.bioactmat.2024.07.023. PMID: 39386222; PMCID: PMC11462046.
Iskhakova K, Cwieka H, Meers S, Helmholz H, Davydok A, Storm M, Baltruschat IM, Galli S, Pröfrock D, Will O, Gerle M, Damm T, Sefa S, He W, MacRenaris K, Soujon M, Beckmann F, Moosmann J, O'Hallaran T, Guillory II RJ, Wieland DCF, Zeller-Plumhoff B, Willumeit-Römer R. Multi-modal investigation of the bone micro- and ultrastructure, and elemental distribution in the presence of Mg-xGd screws at mid-term healing stages. Bioact Mater. 2024 Sep 3;41:657-671. doi: 10.1016/j.bioactmat.2024.07.019. PMID: 39296873; PMCID: PMC11408010.
Halim A, Mondal SK, Al-Qadi N, Kenyon E, MacRenaris K, O'Halloran TV, Medarova Z, Moore A. Monitoring of Nanodrug Accumulation in Murine Breast Cancer Metastases. J Vis Exp. 2024 Aug 23;(210). doi: 10.3791/66961. PMID: 39248512.
Jiang Y, MacRenaris K, O'Halloran TV, Hu J. Determination of metal ion transport rate of human ZIP4 using stable zinc isotopes. J Biol Chem. 2024 Aug 9:107661. doi: 10.1016/j.jbc.2024.107661. Epub ahead of print. PMID: 39128710.
Pawelec KM, Hix JML, Troia A, MacRenaris KW, Kiupel M, Shapiro EM. In vivo micro-computed tomography evaluation of radiopaque, polymeric device degradation in normal and inflammatory environments. Acta Biomater. 2024 Jun;181:222-234. doi: 10.1016/j.actbio.2024.04.031. Epub 2024 Apr 20. PMID: 38648912; PMCID: PMC11144086.
Shapiro JS, Chang HC, Tatekoshi Y, Zhao Z, Waxali ZS, Hong BJ, Chen H, Geier JA, Bartom ET, De Jesus A, Nejad FK, Mahmoodzadeh A, Sato T, Ramos-Alonso L, Romero AM, Martinez-Pastor MT, Jiang SC, Sah-Teli SK, Li L, Bentrem D, Lopaschuk G, Ben-Sahra I, O'Halloran TV, Shilatifard A, Puig S, Bergelson J, Koivunen P, Ardehali H. Iron Drives Anabolic Metabolism Through Active Histone Demethylation and mTORC1.Nat Cell Biol. 2023 Oct; 25(10):1478-1494. PMID: 37749225
Jiang, Yuhan; Li, Zhen; Sui, Dexin; Sharma, Gaurav; Wang, Tianqi; MacRenaris, Keith; Takahashi, Hideki; Merz, Kenneth; Hu, Jian. Rational engineering of an elevator-type metal transporter ZIP8 reveals a conditional selectivity filter critically involved in determining substrate specificity. Communications Biology 2023 Jul 26; 6 (1) 778. PMID: 37495662; PMCID: PMC10372143
Chen Y, Chen S, Ok K, Duncan FE, O’Halloran TV, Woodruff TK. Zinc dynamics regulate early ovarian follicle development. JBC 2023 299(1): 102731. PMID: 36423685; PMCID: PMC9800340;
Chowdhury MAZ, Ok K, Luo Y, Liu Z, Chen S, O'Halloran TV, Kettimuthu R, Tekawade A. ROI-Finder: machine learning to guide region-of-interest scanning for X-ray fluorescence microscopy. J Synchrotron Research 2022 Nov 1;29 (Pt 6): 1495-1503. PMID: 36345757; PMCID: PMC9641565
Rong Q, Lee Y, Tang Y, Vu T, Taboada C, Zheng W, Xia J, Czaplewski DA, Zhang HF, Sun, C, Yao, J. High-Frequency 3D Photoacoustic Computed Tomography Using an Optical Microring Resonator. BME Frontiers 2022 Aug. https://doi.org/10.34133/2022/9891510
Song K, Brenner B, Yeo W, Kweon J, Cai Z, Zhang Y, Lee Y, Yang X, Sun C, Zhang HF. Monolithic dual-wedge prism-based spectroscopic single-molecule localization microscopy. Nanophotonics 2022 11(8), 1527-1535. PMCID: PMC9307059
Zee DZ, MacRenaris KW, O'Halloran TV. Quantitative imaging approaches to understanding biological processing of metal ions. Curr Opin Chem Biol. 2022 69: 102152. PMID: 35561425
Mendoza AD, Sue A, Antipova O, Vogt S, Woodruff TK, Wignall SM, O'Halloran TV. Dynamic zinc fluxes regulate meiotic progression in Caenorhabditis elegans. Biology of Reproduction August 2022 107(2). 406-418. PMID: 35466369
Seeler JF, Sharma A, Zaluzec NJ, Bleher R, Lai B, Schultz EG, Hoffman BM, LaBonne C, Woodruff TK, O'Halloran TV. Metal ion fluxes controlling amphibian fertilization. Nature Chemistry. 2021 Jul;13(7): 683-691. PMID: 34155376; PMCID: PMC8475775
Cai Z, Zhang Y, Zhang Z, Song KH, Beckmann L, Djalilian A, Sun C, Zhang HF. Super-resolution imaging of flat-mounted whole mouse cornea. Exp Eye Res. 2021 Apr;205:108499. PMID: 33610603; PMCID: PMC8043998
Huang J, Ware HOT, Hai R, Shao G, Sun C. Conformal Geometry and Multimaterial Additive Manufacturing through Freeform Transformation of Building Layers. Advanced Materials. 2021 Mar;33(11):e2005672. PMID: 33533141; PMCID: PMC8245009